Table 3. Meta-analysis of factors associated with individual-level ACT coverage for children younger than 5 years with a fever and Plasmodium falciparum infection, in all children and those for whom treatment was sought.
All children with fever and positive RDT | All children with fever and positive RDT for whom treatment was sought | |||||
---|---|---|---|---|---|---|
Number of surveys | Summary OR (95% CI) | p value | Number of surveys | Summary OR (95% CI) | p value | |
Age of child (>2 years vs ≤2 years) | 73 | 1.09 (1.01–1.17) | 0.0205 | 59 | 1.30 (1.20–1.40) | <0.0001 |
Caregiver's education (any vs none) | 72 | 1.31 (1.22–1.41) | <0.0001 | 58 | 1.24 (1.13–1.36) | <0.0001 |
Household wealth (above vs below national median wealth index) | 73 | 1.26 (1.16–1.39) | <0.0001 | 59 | 1.13 (0.99–1.27) | 0.0530 |
Household insecticide-treated net ownership (yes vs no) | 72 | 1.21 (1.13–1.29) | <0.0001 | 57 | 1.16 (1.07–1.27) | 0.0005 |
Area of residence (urban vs rural) | 70 | 1.18 (1.06–1.31) | 0.0020 | 56 | 1.11 (0.97–1.27) | 0.1329 |
PfPR2–10 | 73 | 1.12 (1.02–1.23) | 0.0193 | 59 | 1.20 (1.08–1.33) | 0.0006 |
Health care (public vs private or other) | NA | NA | NA | 54 | 3.18 (2.67–378) | <0.0001 |
Results of meta-analyses of individual survey-dataset-level regressions on ACT coverage for all children with fever and positive RDT results, and in the subgroup of those for whom treatment was sought. Surveys were excluded if fewer than five children who participated took an ACT. The number of surveys per parameter varied because for some surveys no variability was seen in that parameter. Multiple Indicator Cluster Surveys were excluded from the data of those who did seek treatment because they did not include information on where fever treatment was sought. RDT=rapid diagnostic test. ACT=artemisinin-based combination therapy. OR=odds ratio. PfPR2–10=mean (logit-transformed) P falciparum prevalence in children aged 2–10 years. NA=not applicable. PfPR2–10=mean (logit-transformed) Plasmodium falciparum prevalence in children aged 2–10 years.