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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Lancet Glob Health. 2017 Apr;5(4):e418–e427. doi: 10.1016/S2214-109X(17)30076-1

Table 3. Meta-analysis of factors associated with individual-level ACT coverage for children younger than 5 years with a fever and Plasmodium falciparum infection, in all children and those for whom treatment was sought.

All children with fever and positive RDT All children with fever and positive RDT for whom treatment was sought
Number of surveys Summary OR (95% CI) p value Number of surveys Summary OR (95% CI) p value
Age of child (>2 years vs ≤2 years) 73 1.09 (1.01–1.17) 0.0205 59 1.30 (1.20–1.40) <0.0001
Caregiver's education (any vs none) 72 1.31 (1.22–1.41) <0.0001 58 1.24 (1.13–1.36) <0.0001
Household wealth (above vs below national median wealth index) 73 1.26 (1.16–1.39) <0.0001 59 1.13 (0.99–1.27) 0.0530
Household insecticide-treated net ownership (yes vs no) 72 1.21 (1.13–1.29) <0.0001 57 1.16 (1.07–1.27) 0.0005
Area of residence (urban vs rural) 70 1.18 (1.06–1.31) 0.0020 56 1.11 (0.97–1.27) 0.1329
PfPR2–10 73 1.12 (1.02–1.23) 0.0193 59 1.20 (1.08–1.33) 0.0006
Health care (public vs private or other) NA NA NA 54 3.18 (2.67–378) <0.0001

Results of meta-analyses of individual survey-dataset-level regressions on ACT coverage for all children with fever and positive RDT results, and in the subgroup of those for whom treatment was sought. Surveys were excluded if fewer than five children who participated took an ACT. The number of surveys per parameter varied because for some surveys no variability was seen in that parameter. Multiple Indicator Cluster Surveys were excluded from the data of those who did seek treatment because they did not include information on where fever treatment was sought. RDT=rapid diagnostic test. ACT=artemisinin-based combination therapy. OR=odds ratio. PfPR2–10=mean (logit-transformed) P falciparum prevalence in children aged 2–10 years. NA=not applicable. PfPR2–10=mean (logit-transformed) Plasmodium falciparum prevalence in children aged 2–10 years.