Asymptotic regression model coefficient estimates for D. typus and T. mossambicanus normal plasma clotting times. In this example, ϕ1 is the asymptote as x (concentration) approaches ∞, ϕ2 is the response at x = 0, and t0.5 is the half-life. Parameter ϕ3 is the logarithm of the rate constant which is used to enforce positivity so that an asymptote is reached in the model. The corresponding half-life is written t0.5 = log2/exp(ϕ3). Analysis and output performed in R Studio (refer to methodology 4.4.3 Coagulation Statistical analysis).