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Detection of BoNT/A in plasma over time. In an experiment similar to the one shown in Figure 4, the 4-mAb:FP complex, bound to 200 ng BoNT/A (40,000 LD50), was injected i.v. into Swiss Webster mice. RI-BoNT/A in plasma was tested by ELISA at 5, 20, 40, 80, and 160 min in groups with 5 mice each. Control: dilution buffer only. Error bars indicate the S.E.M.
