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The effect of IBET treatment on the mRNA level of p27cip/kip. BON cells were treated with either control DMSO or IBET (500 nM) for 5 days, followed by isolation of RNA from the cells, and qRT-PCR analysis for the FOXO1 and p27 (B). The means of the different groups in the mRNA level were compared using one-way ANOVA test. Differences were considered statistically significant when P < 0.05(*P < 0.05).
