Table I.
Association between miR-137 expression and clinicopathological characteristics in osteosarcoma.
| Variables | Total cases (n=58) | Low miR-137 (n=31) | High miR-137 (n=27) | P-value |
|---|---|---|---|---|
| Age, years | 0.599 | |||
| <20 | 24 | 14 | 10 | |
| ≥20 | 34 | 17 | 17 | |
| Gender | 0.426 | |||
| Male | 35 | 17 | 18 | |
| Female | 23 | 14 | 9 | |
| Tumor size, cm | 0.428 | |||
| <8 cm | 26 | 12 | 14 | |
| ≥8 cm | 32 | 19 | 13 | |
| Location | 0.403 | |||
| Femur or Tibia | 39 | 19 | 20 | |
| Others | 19 | 12 | 7 | |
| Lung metastasis | 0.022a | |||
| No | 40 | 17 | 23 | |
| Yes | 18 | 14 | 4 | |
| TNM stage | 0.029a | |||
| I/IIA | 21 | 7 | 14 | |
| IIB/III | 37 | 24 | 13 | |
| Serum lactate dehydrogenase | 0.788 | |||
| Normal | 22 | 11 | 11 | |
| Elevated | 36 | 20 | 16 | |
| Serum alkaline phosphatase | 0.79 | |||
| Normal | 24 | 12 | 12 | |
| Elevated | 34 | 19 | 15 |
a
P<0.05, representing a statistically significant difference. TNM, tumor-node-metastasis.