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Immunohistochemical analysis of HIF-2α, VEGFA, EphA2 and CD31 expression. The staining indicates protein levels in tumor tissue of (A-D) the control group vs. residual hepatic tumor tissue of (E-H) the experimental group one month after HIFU treatment. Magnification, ×200. HIF-2α, hypoxia-inducible factor-2α; VEGFA, vascular endothelial growth factor A; EphA2, ephrin A2 receptor; CD31, cluster of differentiation 31; HIFU, high intensity focused ultrasound.
