Figure 5.
Effect of HDW on apoptosis-related proteins. WEHI-3 cells treated with HDW at 0.4, 0.8 and 1.6 mg/ml for 48 h. (A) The protein expression of PARP, and caspase-3, −8, and −9 was measured by western blotting. (B) The protein expression of Bcl-2, Bcl-xL and survivin was measured by western blotting. (C) The protein expression of Bak and Bid was also measured by western blotting. Western blot data presented are representative of those obtained in at least three separate experiments. HDW, Hedyotis diffusa Willd; PARP, poly adenosine diphosphate ribose polymerase; Bcl, B-cell lymphoma; xL, extra large; t-Bid, truncated Bid.
