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. 2017 May 4;13(6):3223–3230. doi: 10.3892/etm.2017.4420

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Copyright: © Qiao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Hematoxylin and eosin staining of kidney sections from diabetic rats with and without RSV treatment. (A) Normal glomerulus and tubules of an NG rat. (B) Glomerulus and tubules of a DM rat. Glomerular thickening, interstitial fibrosis and hyaline changes, epithelial cellular vacuolar degeneration, hyaline casts and arteriolopathy are visible. (C) Glomerulus and tubules of a DM rat treated with DMSO vehicle control. Histological alterations of glomeruli and arterioles are similar to those observed in the DM group. (D) Glomerulus and tubules of a DM rat treated with RSV. Milder histological alterations of glomeruli and arterioles are observed. Magnification, ×400. NG, normal control group; DM, diabetes mellitus control group; DM + DMSO, diabetic rats treated with vehicle; DM + RSV, diabetic rats treated with RSV. The dark blue color represents the nuclei and the pink color represents cytoplasm, fibronectin and red blood cells.