Table I.
Effects of resveratrol on basic biochemical parameters in study rats (n=10 per group).
| Parameter | NG | DM | DM + DMSO | DM + RSV |
|---|---|---|---|---|
| Food intake (g/d) | 108.56±8.23 | 210.43±11.97a | 230.55±17.19a | 123.57±9.05a–c |
| Water intake (ml/d) | 250.12±15.03 | 950.66±36.89a | 930.51±27.71a | 380.49±20.01a–c |
| Urine output (ml/d) | 157.21±6.01 | 965.42±21.58a | 872.30±25.34a | 350.48±9.18a–c |
| Blood glucose (mM) | 4.64±0.68 | 26.32±7.78a | 25.99±8.32a | 18.85±5.64a–c |
| Serum creatinine (mM) | 30.24±4.56 | 58.21±8.11a | 59.76±9.03a | 46.62±7.08a–c |
| Urinary albumin (mg/dl) | 4.09±0.52 | 12.89±0.96a | 12.38±0.89a | 8.36±0.45a–c |
| Body weight (g) | 458.25±11.97 | 338.06±10.38a | 347.77±15.37a | 361.05±12.45a |
| Kidney weight (g) | 2.64±0.26 | 3.31±0.19a | 3.48±0.11a | 2.92±0.23a–c |
| Kidney weight/body weight (g/kg) | 5.89±0.11 | 10.09±0.13a | 10.15±0.09a | 7.93±0.18a–c |
NG, normal control group; DM, diabetes mellitus control group; DM + DMSO, diabetic rats treated with vehicle; DM + RSV, diabetic rats treated with RSV.
a
P<0.05 vs. NG
b
P<0.05 vs. DM.
c
P<0.05 vs. DM + DMSO.