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Results of histopathological examination of kidneys of rats in all experimental groups.
| Feature | NG | DM | DM + DMSO | DM + RSV |
|---|---|---|---|---|
| Apical blebbing | − | +++ | +++ | + |
| Glomerular thickening | − | +++ | +++ | + |
| Interstitial fibrosis | − | +++ | +++ | + |
| Arteriolopathy | − | +++ | +++ | + |
| Hyaline casts | − | ++ | ++ | − |
NG, normal control group; DM, diabetes mellitus control group; DM + DMSO, diabetic rats treated with vehicle; DM + RSV, diabetic rats treated with RSV; -, none; +, mild; ++, moderate; +++, severe.
