Table II.

Factors associated with the decline of LS values in uni- and multivariate analyses in group 0.

Factor	Univariate coefficient	P-value	Multivariate coefficient	P-value
Gender	−1.055a	0.292
Age, years	0.068	0.480
Family HBV infection history	−0.236a	0.813
Initial AST	0.154	0.106
Initial ALT	0.166	0.082
Initial TBIL	−0.019	0.845
Initial LS	0.856	<0.001	0.862	<0.001
Initial qHBsAg	−0.130	0.173
Initial AFP	0.320	0.001	0.007	0.901
HBeAg	−0.063	0.510
Initial HBV DNA (log IU/ml)	0.126	0.187
Initial PTA	−0.064	0.503
Therapy before initial LSM	−0.258	0.006	0.016	0.772
Changes of HBV DNA	0.268	0.005	0.057	0.300
Initial platelets	−0.094	0.327
Initial Cr	0.060	0.535
Initial BUN	−0.205	0.031	−0.047	0.364
Initial ALB	−0.207	0.029	0.095	0.097
Initial triglycerides	0.128	0.182

^aMann-Whitney U test. Values are expressed as the mean ± standard deviation. qHBsAg, quantitative hepatitis B surface antigen; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBIL, total bilirubin; AFP, α-fetoprotein; PTA, prothrombin time activity; Cr, creatinine; BUN, blood urea nitrogen; ALB, albumin; HBV, hepatitis B virus; LSM, liver stiffness measurement; LS, liver stiffness.