Table III.
Factors associated with the decline of LS values in uni- and multivariate analyses in group 1.
| Factor | Univariate coefficient | P-value | Multivariate coefficient | P-value |
|---|---|---|---|---|
| Gender | −1.570a | 0.116 | ||
| Age (years) | −0.180 | 0.112 | ||
| Family HBV infection history | −0.148a | 0.883 | ||
| Initial AST | 0.021 | 0.885 | ||
| Initial ALT | 0.006 | 0.960 | ||
| Initial TBIL | −0.233 | 0.038 | −0.166 | 0.156 |
| Initial LS | 0.280 | 0.012 | 0.420 | <0.001 |
| Initial qHBsAg | −0.011 | 0.926 | ||
| Initial AFP | 0.086 | 0.453 | ||
| HBeAg | −0.050 | 0.665 | ||
| Initial HBV DNA | 0.032 | 0.779 | ||
| Initial PTA | 0.239 | 0.034 | 0.315 | 0.013 |
| Therapy before initial LSM | 0.100 | 0.380 | ||
| Changes of HBV DNA | 0.045 | 0.695 | ||
| Initial platelets | 0.053 | 0.640 | ||
| Initial Cr | 0.008 | 0.942 | ||
| Initial BUN | 0.250 | 0.026 | 0.117 | 0.255 |
| Initial ALB | −0.033 | 0.770 | ||
| Initial triglycerides | 0.044 | 0.702 |
a
Mann-Whitney U test. qHBsAg, quantitative hepatitis B surface antigen; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBIL, total bilirubin; AFP, α-fetoprotein; PTA, prothrombin time activity; Cr, creatinine; BUN, blood urea nitrogen; ALB, albumin; HBV, hepatitis B virus; LSM, liver stiffness measurement, LS, liver stiffness.