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. 2016 Dec 10;2016(12):CD004246. doi: 10.1002/14651858.CD004246.pub4

Comparison 3. Efavirenz versus nevirapine: subgroup analyses for concurrent TB treatments.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Virological success 9 2369 Risk Ratio (M‐H, Random, 95% CI) 1.04 [0.99, 1.10]
1.1 Concurrent treatment for TB 4 963 Risk Ratio (M‐H, Random, 95% CI) 1.08 [0.99, 1.18]
1.2 No treatment for TB 5 1406 Risk Ratio (M‐H, Random, 95% CI) 1.01 [0.95, 1.08]
2 Mortality 8 2317 Risk Ratio (M‐H, Random, 95% CI) 0.84 [0.59, 1.19]
2.1 Concurrent treatment for TB 4 963 Risk Ratio (M‐H, Random, 95% CI) 0.69 [0.40, 1.19]
2.2 No treatment for TB 4 1354 Risk Ratio (M‐H, Random, 95% CI) 1.01 [0.62, 1.64]
3 Progression to AIDS 5 2005 Risk Ratio (M‐H, Random, 95% CI) 1.23 [0.72, 2.11]
3.1 Concurrent treatment for TB 2 712 Risk Ratio (M‐H, Random, 95% CI) 1.09 [0.62, 1.92]
3.2 No treatment for TB 3 1293 Risk Ratio (M‐H, Random, 95% CI) 1.51 [0.44, 5.16]
4 Discontinuation rate 9 2384 Risk Ratio (M‐H, Random, 95% CI) 0.93 [0.69, 1.25]
4.1 Concurrent treatment for TB 4 963 Risk Ratio (M‐H, Random, 95% CI) 0.92 [0.59, 1.42]
4.2 No treatment for TB 5 1421 Risk Ratio (M‐H, Random, 95% CI) 0.99 [0.63, 1.55]