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. 2016 Dec 13;2016(12):CD006519. doi: 10.1002/14651858.CD006519.pub3

Bhan 1987.

Methods RCT
Generation of allocation sequence: randomly assigned using sealed envelopes
Allocation concealment: sealed envelopes
Blinding: none
Inclusion of participants in analysis: > 90%
Duration: not specified; only stated that trial was done for 10 consecutive months
Participants Number of participants: 93 enrolled
Inclusion criteria: males; age 3 months to 5 years; watery diarrhoea < 5 days; presence of dehydration; weight for height > 70% of 50th centile of reference standard
Exclusion criteria: female; persistent vomiting; bloody diarrhoea; temperature > 39°C; other associated medical illness; intake of antibiotics during illness
Interventions
  • Glucose ORS: 33 participants.

  • Pop rice ORS: 31 participants.

  • Mung bean ORS: 29 participants.

Outcomes
  • Total stool output in first 24 hours.

  • Total stool output from randomization to discharge.

  • Duration of diarrhoea.

  • Number of participants with unscheduled use of intravenous fluid.

  • Number of participants with vomiting.

Glucose‐based ORS osmolarity ≥ 310 mOsm/L
Setting Hospital‐based trial
Location: New Delhi, India
Notes Participants who were given glucose ORS were more malnourished as compared to the treatment groups, but the difference was not statistically significant
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk RCT: randomly assigned using sealed envelopes
Allocation concealment (selection bias) Unclear risk Sealed envelopes
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Participants, providers, and outcome assessors were not blinded
Blinding of outcome assessment (detection bias) 
 All outcomes High risk Participants, providers, and outcome assessors were not blinded
Incomplete outcome data (attrition bias) 
 All outcomes Low risk The trial included all randomized participants in the analysis
Selective reporting (reporting bias) Low risk The trial reported over 90% of the included participants in the final analysis
Other bias Unclear risk We did not detect any other sources of bias