Bhan 1987.
Methods | RCT Generation of allocation sequence: randomly assigned using sealed envelopes Allocation concealment: sealed envelopes Blinding: none Inclusion of participants in analysis: > 90% Duration: not specified; only stated that trial was done for 10 consecutive months |
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Participants | Number of participants: 93 enrolled Inclusion criteria: males; age 3 months to 5 years; watery diarrhoea < 5 days; presence of dehydration; weight for height > 70% of 50th centile of reference standard Exclusion criteria: female; persistent vomiting; bloody diarrhoea; temperature > 39°C; other associated medical illness; intake of antibiotics during illness |
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Interventions |
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Outcomes |
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Glucose‐based ORS osmolarity | ≥ 310 mOsm/L | |
Setting | Hospital‐based trial Location: New Delhi, India |
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Notes | Participants who were given glucose ORS were more malnourished as compared to the treatment groups, but the difference was not statistically significant | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | RCT: randomly assigned using sealed envelopes |
Allocation concealment (selection bias) | Unclear risk | Sealed envelopes |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Participants, providers, and outcome assessors were not blinded |
Blinding of outcome assessment (detection bias) All outcomes | High risk | Participants, providers, and outcome assessors were not blinded |
Incomplete outcome data (attrition bias) All outcomes | Low risk | The trial included all randomized participants in the analysis |
Selective reporting (reporting bias) | Low risk | The trial reported over 90% of the included participants in the final analysis |
Other bias | Unclear risk | We did not detect any other sources of bias |