Ramakrishna 2008.

Methods	RCT Generation of allocation sequence: table of random numbers Allocation concealment: serially numbered ORS packages Blinding: assessors but not the participants or providers were blinded because of the nature of the study Inclusion of participants in analysis: 100% Duration: not stated
Participants	Number of participants: 50 enrolled Inclusion criteria: males; 18 to 65 years old; acute watery diarrhoea Exclusion criteria: presence of bloody diarrhoea; presence of systemic illness
Interventions	Glucose ORS: 25 participants. Amylase‐resistant starch ORS: 25 participants.
Outcomes	Total stool output (g) in first 24 hours. Duration of diarrhoea. Unscheduled use of intravenous fluid. Number of participants with hyponatraemia.
Glucose‐based ORS osmolarity	≤ 270 mOsm/L
Setting	Hospital‐based trial Location: Vellore, India
Notes	—
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	RCT: Table of random numbers
Allocation concealment (selection bias)	Low risk	Serially numbered ORS packages
Blinding of participants and personnel (performance bias) All outcomes	High risk	Participants and providers were not blinded because of the nature of the study
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Outcome assessors were blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	The trial included all randomized participants in the analysis
Selective reporting (reporting bias)	Low risk	The trial reported over 90% of the included participants in the final analysis
Other bias	Unclear risk	We did not detect any other sources of bias