Table 3. Frequencies of essential versus viable mouse genes expressed at different developmental stages in the non-culled dataset.
The p-value for the Bonferroni correction is 0.00385.
| Developmental stage | Essential (%) | Viable (%) | p-value |
|---|---|---|---|
| Oocyte | 42.0 | 20.9 | 3.6×10−36 |
| Unfertilized Ovum | 26.3 | 10.5 | 5.9×10−36 |
| Zygote | 35.3 | 17.8 | 2.9×10−29 |
| Cleavage | 45.5 | 23.2 | 3.0×10−36 |
| Morula | 43.6 | 19.7 | 2.2×10−46 |
| Blastocyst | 59.8 | 30.4 | 1.2×10−47 |
| Egg Cylinder | 22.4 | 8.3 | 6.0×10−35 |
| Gastrula | 57.1 | 29.3 | 8.1×10−45 |
| Organogenesis | 83.8 | 54.1 | 1.0×10−30 |
| Fetus | 97.3 | 86.4 | 4.3×10−4 |
| Neonate | 85.0 | 70.7 | 5.1×10−7 |
| Juvenile | 92.4 | 87.8 | 0.14 |
| Adult | 95.9 | 94.1 | 0.56 |