Table 8. Frequencies (%) of post-translational and transcription keywords in essential and viable mouse proteins and the corresponding p-values computed using the Chi-square test.

The Bonferroni corrected p-value is 0.0125.

Datasets		Keywords
		Phosphoprotein	Glycoprotein	Acetylation	Transcription
Non-culled	Essential	51.4	21.3	28.9	27.8
	Viable	35.5	38.2	12.9	11.5
	p-value	8.9×10−15	3.1×10−19	4.5×10−33	1.8×10−36
Culled (20%)	Essential	40.5	20.0	30.7	15.9
	Viable	29.2	33.2	16.3	7.9
	p-value	3.7×10−4	9.9×10−6	1.5×10−8	7.8×10−6
Culled (40%)	Essential	52.7	21.1	31.3	21.2
	Viable	32.7	38.1	13.6	9.6
	p-value	6.3×10−17	1.6×10−14	2.8×10−26	3.5×10−17
Culled (60%)	Essential	52.3	21.4	29.7	26.1
	Viable	34.6	38.8	12.7	11.1
	p-value	1.3×10−16	9.3×10−19	2.3×10−33	1.7×10−29
Culled (80%)	Essential	51.5	21.2	28.9	27.7
	Viable	35.4	38.4	12.6	11.5
	p-value	5.7×10−15	9.5×10−20	1.8×10−33	1.5×10−35