Table 9. Signal peptide count in essential and viable proteins and the corresponding p–values computed using the Chi–square test.

Datasets	Essential	Viable	%Essential	%Viable	p-value
Non-culled	213	1004	16.4	29.1	1.2×10−19
Culled (20%)	67	304	14.0	29.9	8.3×10−9
Culled (40%)	151	698	15.7	30.3	8.8×10−14
Culled (60%)	200	941	16.5	30.3	1.8×10−15
Culled (80%)	210	993	16.3	29.3	4.1×10−15