Table 10. Top 20 enriched cellular component GO terms associated with essential mouse genes.
GO Term ID | GO Term Annotation | Count | % | Bonferroni Corrected p-Values |
---|---|---|---|---|
GO:0005634 | nucleus | 747 | 57.8 | 9.7x10-95 |
GO:0005667 | transcription factor complex | 104 | 8.04 | 1.4x10-50 |
GO:0005654 | nucleoplasm | 309 | 23.8 | 2.6x10-50 |
GO:0005737 | cytoplasm | 682 | 52.7 | 9.4x10-46 |
GO:0043234 | protein complex | 126 | 9.7 | 1.4x10-27 |
GO:0005829 | cytosol | 239 | 18.5 | 5.8x10-22 |
GO:0000790 | nuclear chromatin | 64 | 4.9 | 1.3x10-20 |
GO:0005925 | focal adhesion | 77 | 6.0 | 5.5x10-15 |
GO:0048471 | perinuclear region of cytoplasm | 103 | 8.0 | 4.9x10-12 |
GO:0009986 | cell surface | 97 | 7.5 | 5.4x10-12 |
GO:0005911 | cell-cell junction | 45 | 3.5 | 6.6x10-10 |
GO:0043025 | neuronal cell body | 80 | 6.2 | 4.9x10-9 |
GO:0043005 | neuron projection | 68 | 5.3 | 6.9x10-9 |
GO:0005730 | nucleolus | 107 | 8.3 | 8.3x10-8 |
GO:0030424 | axon | 60 | 4.6 | 1.1x10-7 |
GO:0000785 | chromatin | 31 | 2.4 | 5.0x10-7 |
GO:0030054 | cell junction | 90 | 7.0 | 2.0x10-6 |
GO:0005694 | chromosome | 54 | 4.2 | 2.7x10-6 |
GO:0043231 | intracellular membrane-bounded organelle | 93 | 7.2 | 2.9x10-6 |
GO:0017053 | transcriptional repressor complex | 20 | 1.5 | 3.4x10-6 |