Table 13. Subcellular locations of all essential and viable mouse proteins, which were predicted by WoLF PSORT.

p–values were computed using the Chi–square test. Here, the Bonferroni corrected p-value = 0.0056.

Cellular Components	Essential	Viable	%Essential	%Viable	p-value
Nucleus	921	1712	70.8	49.6	2.2×10−18
Cytoplasm	700	1556	53.8	45.1	1.0×10−4
Plasma membrane	307	1261	23.6	36.5	4.3×10−12
Extracellular	353	1377	27.1	39.9	7.8×10−11
Mitochondrion	321	890	24.7	25.8	0.50
Endoplasmic Reticulum (ER)	183	621	14.1	18.0	3.3×10−3
Golgi	45	156	3.5	4.5	0.11
Lysosome	86	398	6.6	11.5	2.1×10−6
Peroxisome	204	623	15.7	18.1	0.08