Table 14. Top 20 enriched GO terms for essential mouse genes that are related to biological processes.

GO Term ID	GO Term Annotation	Count	%	Bonferroni Corrected p-Value
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	294	22.7	3.3x10-105
GO:0001701	in utero embryonic development	156	12.1	7.2x10-95
GO:0045893	positive regulation of transcription, DNA-templated	202	15.6	6.9x10-84
GO:0006351	transcription, DNA-templated	365	28.2	3.4x10-75
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	217	16.8	5.8x10-75
GO:0007507	heart development	130	10.1	5.3x10-74
GO:0007275	multicellular organism development	255	19.7	1.5x10-71
GO:0006355	regulation of transcription, DNA-templated	398	30.8	1.4x10-69
GO:0010628	positive regulation of gene expression	112	8.7	1.0x10-33
GO:0008284	positive regulation of cell proliferation	132	10.2	1.9x10-33
GO:0043066	negative regulation of apoptotic process	135	10.4	4.3x10-33
GO:0009887	organ morphogenesis	55	4.3	1.7x10-29
GO:0045892	negative regulation of transcription, DNA-templated	131	10.1	3.6x10-29
GO:0006357	regulation of transcription from RNA polymerase II promoter	105	8.1	7.8x10-29
GO:0009952	anterior/posterior pattern specification	55	4.3	1.0x10-28
GO:0001525	angiogenesis	78	6.0	4.6x10-27
GO:0008285	negative regulation of cell proliferation	100	7.7	1.3x10-26
GO:0003007	heart morphogenesis	41	3.2	1.5x10-26
GO:0001568	blood vessel development	42	3.2	2.6x10-25
GO:0001570	vasculogenesis	41	3.2	4.6x10-25