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. 2017 May 31;12(5):e0178273. doi: 10.1371/journal.pone.0178273

Table 17. Top 20 enriched GO terms for viable mouse genes that are related to molecular function.

GO Term ID GO Term Annotation Count % Bonferroni Corrected p-Value
GO:0005515 protein binding 1242 36.2 3.3x10-93
GO:0004871 signal transducer activity 259 7.6 1.4x10-33
GO:0042803 protein homodimerization activity 293 8.5 1.7x10-30
GO:0005216 ion channel activity 97 2.8 1.2x10-25
GO:0005102 receptor binding 173 5.0 2.5x10-24
GO:0019901 protein kinase binding 170 5.0 2.7x10-19
GO:0004672 protein kinase activity 192 5.6 1.4x10-18
GO:0046982 protein heterodimerization activity 188 5.5 8.1x10-18
GO:0016301 kinase activity 221 6.4 9.6x10-16
GO:0005125 cytokine activity 95 2.8 2.8x10-14
GO:0042802 identical protein binding 215 6.3 3.1x10-14
GO:0043565 sequence-specific DNA binding 198 5.8 4.1x10-11
GO:0008083 growth factor activity 67 2.0 3.1x10-10
GO:0004872 receptor activity 75 2.2 5.4x10-10
GO:0002020 protease binding 58 1.7 6.4x10-10
GO:0019899 enzyme binding 134 3.9 9.1x10-10
GO:0008201 heparin binding 67 2.0 6.7x10-9
GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding 99 2.9 1.9x10-8
GO:0008144 drug binding 54 1.6 4.3x10-8
GO:0004896 cytokine receptor activity 30 0.9 4.7x10-8