Table 17. Top 20 enriched GO terms for viable mouse genes that are related to molecular function.
GO Term ID | GO Term Annotation | Count | % | Bonferroni Corrected p-Value |
---|---|---|---|---|
GO:0005515 | protein binding | 1242 | 36.2 | 3.3x10-93 |
GO:0004871 | signal transducer activity | 259 | 7.6 | 1.4x10-33 |
GO:0042803 | protein homodimerization activity | 293 | 8.5 | 1.7x10-30 |
GO:0005216 | ion channel activity | 97 | 2.8 | 1.2x10-25 |
GO:0005102 | receptor binding | 173 | 5.0 | 2.5x10-24 |
GO:0019901 | protein kinase binding | 170 | 5.0 | 2.7x10-19 |
GO:0004672 | protein kinase activity | 192 | 5.6 | 1.4x10-18 |
GO:0046982 | protein heterodimerization activity | 188 | 5.5 | 8.1x10-18 |
GO:0016301 | kinase activity | 221 | 6.4 | 9.6x10-16 |
GO:0005125 | cytokine activity | 95 | 2.8 | 2.8x10-14 |
GO:0042802 | identical protein binding | 215 | 6.3 | 3.1x10-14 |
GO:0043565 | sequence-specific DNA binding | 198 | 5.8 | 4.1x10-11 |
GO:0008083 | growth factor activity | 67 | 2.0 | 3.1x10-10 |
GO:0004872 | receptor activity | 75 | 2.2 | 5.4x10-10 |
GO:0002020 | protease binding | 58 | 1.7 | 6.4x10-10 |
GO:0019899 | enzyme binding | 134 | 3.9 | 9.1x10-10 |
GO:0008201 | heparin binding | 67 | 2.0 | 6.7x10-9 |
GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 99 | 2.9 | 1.9x10-8 |
GO:0008144 | drug binding | 54 | 1.6 | 4.3x10-8 |
GO:0004896 | cytokine receptor activity | 30 | 0.9 | 4.7x10-8 |