Table 21. Distributions of four network properties: BottleNeck (BN), Edge Percolation Component (EPC), Maximum Neighbourhood Component (MNC) and Density of Maximum Neighbourhood Component (DMNC) between essential and viable proteins.
The Bonferroni corrected p-value in the Mann Whitney U test is 0.0125. Here, mean rank indicates which protein group holds higher values for a network property.
| Network | Network Properties | ||||
|---|---|---|---|---|---|
| BN | EPC | MNC | DMNC | ||
| Known (K | Essential (Mean Rank | 1522 | 1520 | 1486 | 1442 |
| Viable (Mean Rank | 1287 | 1288 | 1304 | 1326 | |
| p-valu | 1.0×10−17 | 4.6×10−13 | 5.6×10−10 | 7.2×10−5 | |
| Known-Predicted (KP | Essential (Mean Rank | 2468 | 2683 | 2685 | 2147 |
| Viable (Mean Rank | 2037 | 1950 | 1949 | 2166 | |
| p-valu | 9.1×10−39 | 3.1×10−68 | 2.4×10−69 | 0.641 | |