Table A.8.

Cost of LTBI treatment by 9H or 3HP^*

Category	Cost US$	Source
Initial clinic visit
Personnel cost	110.94	Table A.2
Patient cost	37.05
Supply cost	54.90	Table A.2
Total health system	165.84	Supply cost + personnel cost
Total societal	202.89	Supply cost + personnel cost + patient cost
Follow-up clinic visit
Personnel cost	24.37	Table A.6
Patient cost	21.73
Supply cost	3.56	Table A.2
Total health system	27.92	Supply cost + personnel cost
Total societal	49.65	Supply cost + personnel cost + patient cost
DOT, per dose		Table A.7
Health system	17.76
Societal	19.56
Medication cost, per month on treatment†		Department of Veterans Affairs Pharmaceutical Prime Vendor Program
9H (30 × 300 mg INH)	1.58
3HP (4 × 900 mg INH + 4 × 900 mg RPT)	49.25
9H total treatment cost, per patient completing 270 doses‡		Based on 1 initial clinic visit, 8 monthly follow-up clinic visits, and 9 months of medication
Health system	403.45
Societal	614.32
3HP total treatment cost, per patient completing 12 doses‡		Based on 1 initial clinic visit, 2 monthly follow-up clinic visits, 3 months of medication, and 12 DOT visits
Health system	582.55
Societal	684.71

^*Health system costs do not include costs to the patient; societal costs include all health system costs plus patient costs. Clinic visit costs include supplies, clinic personnel time, and (for the societal perspective only) patient time and bus fare. Medication costs are not included in clinic visit costs.

^†Medication costs are borne by the health system.

^‡LTBI treatment costs for simulated patients depend on the number of doses taken; on average they are less than the cost of completed treatment because of the possibility of non-adherence.

LTBI = latent tuberculous infection; 9H = 9 months of daily, self-administered INH; 3HP = 12-dose regimen of weekly RPT plus INH; INH = isoniazid; RPT = rifapentine.