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. 2017 May 15;127(6):2091–2105. doi: 10.1172/JCI89914

Figure 7. Lipid phenotype of neoadjuvant-treated breast cancers.

Figure 7

Network plot for all reactome pathways under the term “Metabolism of lipids and lipoproteins,” which are significantly deregulated in at least one of 4 assays: MYC/KRAS, MYC/NEU, GSE32072, or RNA-seq. Strong significance threshold for mouse assays, P < 0.005, and human assays, 0.05. Significance threshold for mouse assays, P < 0.05, and human assays, P < 0.1. Pathway significance is colored by its best P value in the mouse assays.