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. Author manuscript; available in PMC: 2017 May 31.
Published in final edited form as: Mol Cancer Res. 2017 Feb 9;15(3):250–258. doi: 10.1158/1541-7786.MCR-16-0132

Figure 4.

Figure 4

Sunitinib and Lys05 induce apoptosis in CCOC. A, Caspase-3/7 activity was determined by treating CCOC cells with 10 μmol/L sunitinib, 10 μmol/L Lys05, or the combination for 48 hours. Etoposide served as a positive control. Graphs, average ± SEM (combined n = 2 of 3 independent experiments, Student t test; *, P<0.05). B, PARP cleavage was assessed following 10 μmol/L sunitinib, 10 μmol/L Lys05, or the combination of the two agents for 48 hours. Etoposide served as a positive control. GAPDH served as a loading control (n = 3). Sut, Sutent.