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Characterization of micelle formulations encapsulating different APIs.
| API | Avg. Diameter (nm) |
Efficiency (%) |
Drug Weight Loading (% wt/wt1) |
Dialysis > CMC (% remaining) |
Dialysis < CMC (% remaining) |
|---|---|---|---|---|---|
| Aminopterin | 70 | 68 | 5.0 | 75 | 65 |
| Daunorubicin | 58 | 82 | 7.2 | 95 | 61 |
| Epothilone D | 75 | 91 | 4.4 | 94 | 68 |
| Paclitaxel | 72 | 65 | 3.0 | 91 | 77 |
| Panobinostat | 80 | 88 | 7.4 | 95 | 93 |
| SN-38 | 120 | 90 | 3.8 | -- | -- |
% wt drug/wt polymer
