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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Pathol Oncol Res. 2016 Dec 26;23(3):673–677. doi: 10.1007/s12253-016-0166-2

Figure 1.

Figure 1

Representative FISH analysis performed on formalin-fixed, paraffin-embedded human colon cancer samples. Dual-color FISH probes contain EGFR (red signals) and centromere of chromosome 7 (green signals). DAPI (blue) was used as counterstain. A shows EGFR gene amplification in human epidermoid carcinoma cell line A-431 with well-documented EGFR gene amplification. B shows colon cancer without EGFR amplification. C and D show colon cancer with EGFR amplification.