Table 2.
Summary of number of significant results and tests per analysis.
Test | # tests | Bonferroni Corrected Thresholda | # passing threshold (SBP) | # passing threshold (DBP) |
---|---|---|---|---|
Common | 28,851 | 1.73 × 10−6 | 0 | 0 |
Low frequency | 17,985 | 2.78 × 10−6 | 0 | 0 |
Rare | 105,487 | 4.74 × 10−7 | 7 | 2 |
Gene-based | 15,554 | 3.21 × 10−6 | 0 | 0 |
T1 (all variants) | 14,465 | 3.46 × 10−6 | 0 | 0 |
T1 (deleterious variants) | 5,024 | 9.95 × 10−6 | 1 | 1 |
SBP, systolic blood pressure; DBP, diastolic blood pressure; # tests, number of variants or genes analyzed
The significance threshold as determined by the Bonferroni method corrects for the number of tests (0.05/# tests) in each analysis.