Table 4.
Burden-T1-del significant genes for SBP and DBP (p<9.95 x 10−6).
| Gene | Test | Trait | p-value | # SNPs analyzed | Cumulative Carrier Count | βsm (SE)a |
|---|---|---|---|---|---|---|
| CCDC13 | Burden-T1-del | SBP | 3.54 × 10−7 | 2 | 2 | 54.38 (10.68) |
| QSOX1 | Burden-T1-del | DBP | 3.86 × 10−6 | 2 | 3 | 32.93 (7.13) |
Burden-T1-del, T1 burden test on deleterious variants with minor allele frequency (MAF)<0.001; # SNPs analyzed, number of SNPs included in test for gene; Cumulative Carrier Count, number of carriers (same as allele count) across all analyzed variants; βsm, seqMeta beta; SE, standard error
The βsm (SE) values are reported from seqMeta output, in units of the phenotype residuals.