Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun;102(6):1044–1053. doi: 10.3324/haematol.2016.161257

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright© Ferrata Storti Foundation

Material published in Haematologica is covered by copyright. All rights are reserved to the Ferrata Storti Foundation. Use of published material is allowed under the following terms and conditions:

https://creativecommons.org/licenses/by-nc/4.0/legalcode. Copies of published material are allowed for personal or internal use. Sharing published material for non-commercial purposes is subject to the following conditions:

https://creativecommons.org/licenses/by-nc/4.0/legalcode, sect. 3. Reproducing and sharing published material for commercial purposes is not allowed without permission in writing from the publisher.

PMC Copyright notice

Figure 3. — Comparison of expression patterns, clinical and biological features among subgroups of NTUH AML patients based on hierarchical clustering of HOPX and HOX family genes. (A) Heatmap of HOPX and HOX family genes in NTUH data. We identify 4 groups of patients based on a 2-step hierarchical clustering: HOX^high/HOPX^low by HOPX^high/HOPX^low. Molecular and clinical variables including gene mutations, cytogenetic abnormalities, and leukemia classifications are compared among the clusters. (B) Average z-scores of HOPX and HOX genes in each group. Whiskers denote average±standard deviation of the z-scores. Statistical significance of the z-scores against zero is assessed by the 1-sample t-test (****P<0.0001). (C) Overall survival of the 4 groups of patients. HOX^low/HOPX^low patients have the best overall survival (OS), followed by HOX^low/HOPX^high, HOX^high/HOPX^low, and HOX^high/HOPX^high (P<0.001).