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. 2017 Jun;102(6):1091–1098. doi: 10.3324/haematol.2016.156885

Figure 3.

Figure 3.

ID3, TCF3, Cyclin D3 pathway with frequencies of respective mutations in MYC rearrangement positive BL. BL with positive MYC translocation had mutations in at least one of the three investigated candidate genes in 89%, representing affection of the ID3-TCF3-CCND3 pathway in the vast majority of pediatric BL cases.