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Clonal architecture of (pre)leukemic and leukemic cells in patient UPN1300. A proportional scheme of distinct subclones bearing different aberrations (A–E) and their relative representation within the population of (pre)leukemic cells in bone marrow taken 3 months before leukemia onset and at diagnosis. Only cells harboring the ETV6-RUNX1 fusion were considered as (pre)leukemic and further analyzed.
