. 2017 May 31;7:2549. doi: 10.1038/s41598-017-02352-5

Table 1.

Integrins described as HSPC related.

Integrin	CD	Gene Name	Ligands (in heterodimeres)	HSPC Function
α4	CD49d	ITGA4	Fibronectin VCAM-1	BM homing, BM engraftment, maintenance blocking leads to mobilization^{35, 63}
α5	CD49e	ITGA5	Fibronectin Osteopontin	BM lodgement via osteopontin binding^{64, 65}
α6	CD49f	ITGA6	Laminin	Blocking leads to reduced BM homing⁶⁶
αIIb	CD41	ITGAIIb	Fibronectin	Early hematopoiesis, BM logement, regulation of progenitor number^67–69
αV	CD51	ITGAV	Fibronectin Vitronectin Tenascin	Maintenance³⁷
β1	CD29	ITGB1	Collagen Laminin Fibronectin Osteopontin	BM lodgement, Differentiation^{12, 70}
β3	CD61	ITGB3	Fibronectin	Maintenance^{13, 14, 37}