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. 2017 May 31;7:2510. doi: 10.1038/s41598-017-02820-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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1e compound does not induce proliferation at systemic level in the MITO-Luc mouse. (a) In vivo whole body bioluminescence imaging of MITO-Luc after indicated treatments. Photos portray whole body (ventral view) at 0, 24, 48, 72 hours after treatments in a pseudocolor image processed to indicating the intensity of photon emission in whole body. (b) In vivo BLI: photon emission from selected body areas were measured. Bars represent the mean ratio versus t = 0 h and vs vehicle ± SEM of photon emission measured in 4 animals/group.