Figure 6.

Increased levels of FXYD5 are sufficient to recruit CCR2⁺ classical monocytes to the lung. (A) Mice were instilled with Ad-FXYD5 and treated with the anti-CCR2 antibody for 24 h prior to the measurements. Total cell count in BALF was determined (n = 5). (B,C) WT and CCR2^−/− mice were instilled like in (A). Total cell counts n = 3 (B) and CCL2 n = 4 (C) were determined in BALF. Values represent means ± SD. Differences between groups were compared using unpaired Student’s t-test or one way ANOVA Sidak’s multiple comparison test. *p ≤ 0.05 **p ≤ 0.01; ***p ≤ 0.001.