Table 1.
Previous meta-analysis characteristics.
| First author | Journal | Year | Comparison | End-points | Number of studies |
|---|---|---|---|---|---|
| Daya | Fertil Steril | 1995 | U-follicle-stimulating hormone (FSH) vs. r-FSH | Pregnancy rate | 8 |
| Daya | Cochrane Database Syst Rev | 1996 | U-FSH vs. r-FSH | Withdrawan | |
| Daya | Hum Reprod | 1999 | U-FSH vs. r-FSH | Oocytes retrieved | 12 |
| Nugent | Cochrane Database Syst Rev | 2000 | Different u-FSH in polycystic ovarian syndrome (PCOS) | Pregnancy rate | 23 |
| Daya | Cochrane Database Syst Rev | 2000 | U-FSH vs. r-FSH | Pregnancy rate | 18 |
| van Wely | Fertil Steril | 2003 | Human menopausal gonadotropin (hMG) vs. r-FSH | Pregnancy rate | 6 |
| Al-Inany | Hum Reprod | 2003 | U-FSH vs. r-FSH | Oocytes retrieved | 20 |
| Albuquerque | Cochrane Database Syst Rev | 2005 | Depot gonadotropin-releasing hormone (GnRH) agonist vs. daily GnRH agonist | Pregnancy rate | 6 |
| Pandian | Cochrane Database Syst Rev | 2005 | In vitro fertilization (IVF) vs. intrauterine insemination (IUI) | Pregnancy rate | 10 |
| Sallam | Cochrane Database Syst Rev | 2006 | GnRH agonist timing in endometriosis | Pregnancy rate | 3 |
| Griesinger | Reprod Biomed Online | 2006 | GnRH agonist vs. GnRH antagonist in PCOS | Oocytes retrieved | 13 |
| Franco | Reprod Biomed Online | 2006 | GnRH agonist vs. GnRH antagonist in PCOS | Oocytes retrieved | 6 |
| Sunkara | Reprod Biomed Online | 2007 | GnRH agonist vs. GnRH antagonist | Oocytes retrieved | 9 |
| Mochtar | Cochrane Database Syst Rev | 2007 | R-luteinizing hormone (LH) plus r-FSH vs. r-FSH | Live birth rate | 14 |
| Pandian | Cochrane Database Syst Rev | 2007 | Different GnRH analog protocols | Live birth rate | 9 |
| Daya | Cochrane Database Syst Rev | 2007 | U-FSH vs. r-FSH | Withdrawan | |
| Kolibianakis | Hum Reprod Update | 2007 | R-LH plus r-FSH vs. r-FSH in GnRH antagonist | Live birth rate | 5 |
| Baruffi | Reprod Biomed Online | 2007 | R-LH plus r-FSH vs. r-FSH in GnRH antagonist | Oocytes retrieved | 5 |
| Al-Inany | Reprod Biomed Online | 2008 | hMG vs. r-FSH | Live birth rate | 10 |
| Coomarasamy | Hum Reprod | 2008 | U-FSH vs. r-FSH | Live birth rate | 7 |
| Al-Inany | Reprod Biomed Online | 2008 | hMG vs. r-FSH | Live birth rate | 5 |
| Al-Inany | Gynecol Endocinol | 2009 | hMG vs. r-FSH | Pregnancy rate | 6 |
| Jee | Gynecol Obstet Invest | 2010 | hMG vs. r-FSH | Pregnancy rate | 10 |
| Lehert | Reprod Biol Endocrinol | 2010 | hMG vs. r-FSH | Oocytes retrieved | 16 |
| Pandian | Cochrane Database Syst Rev | 2010 | GnRH agonist vs. GnRH antagonist | Live birth rate | 15 |
| Pandian | Cochrane Database Syst Rev | 2010 | Different GnRH analog protocols | Live birth rate | 10 |
| Sterrenburg | Hum Reprod Update | 2011 | Different r-FSH doses | Pregnancy rate | 10 |
| Al-Inany | Cochrane Database Syst Rev | 2011 | GnRH agonist vs. GnRH antagonist | Live birth rate | 45 |
| Youssef | Cochrane Database Syst Rev | 2011 | GnRH agonist vs. hCG for trigger | Live birth rate | 11 |
| van Wely | Cochrane Database Syst Rev | 2011 | hMG vs. r-FSH | Live birth rate | 42 |
| Youssef | Cochrane Database Syst Rev | 2011 | U-hCG vs. r-hCG | Live birth rate | 14 |
| Siristatidis | Cochrane Database Syst Rev | 2011 | Different GnRH agonist protocols | Pregnancy rate | 29 |
| Maheshwari | Cochrane Database Syst Rev | 2011 | Short vs. ultra-short GnRH agonist protocols | Pregnancy rate | 29 |
| Pundir | Hum Reprod | 2011 | GnRH agonist vs. GnRH antagonist | Oocytes retrieved | 14 |
| Bodri | Fertil Steril | 2011 | GnRH agonist vs. GnRH antagonist | Pregnancy rate | 8 |
| van Wely | Hum Reprod Update | 2012 | hMG vs. r-FSH | Live birth rate | 42 |
| Hill | Fertil Steril | 2012 | R-LH plus r-FSH vs. r-FSH in GnRH antagonist | Pregnancy rate | 7 |
| Konig | Fertil Steril | 2012 | R-LH plus r-FSH vs. r-FSH in GnRH antagonist in women older than 35 years | Pregnancy rate | 9 |
| Mahmoud Youssef | Fertil Steril | 2012 | Long acting FSH vs. r-FSH | Pregnancy rate | 4 |
| Pandian | Cochrane Database Syst Rev | 2012 | IVF vs. IUI | Pregnancy rate | 6 |
| Gibreel | Cochrane Database Syst Rev | 2012 | Gonadotropins vs. clomiphene citrate | Live birth rate | 14 |
| Pouwer | Cochrane Database Syst Rev | 2012 | Long acting FSH vs. r-FSH | Live birth rate | 4 |
| Pundir | Reprod Biomed Online | 2012 | GnRH agonist vs. GnRH antagonist in PCOS | OHSS rate | 9 |
| Albuquerque | Cochrane Database Syst Rev | 2013 | Depot GnRH agonist vs. daily GnRH agonist | Pregnancy rate | 16 |
| Matsaseng | Gynecol Obstet Invest | 2013 | Mild ovarian stimulations vs. traditional IVF | Pregnancy rate | 5 |
| Xiao | Fertil Steril | 2013 | GnRH agonist vs. GnRH antagonist | Pregnancy rate | 12 |
| Fan | Gynecol Endocinol | 2013 | rLH supplementation in poor responders | Pregnancy rate | 3 |
| Xiao | Gynecol Endocinol | 2013 | GnRH agonist vs. GnRH antagonist | Oocytes retrieved | 7 |
| Youssef | Cochrane Database Syst Rev | 2014 | GnRH agonist vs. hCG for trigger | Live birth rate | 17 |
| Xiao | PlosONE | 2014 | GnRH agonist vs. GnRH antagonist | Oocytes retrieved | 23 |
| Chen | Gynecol Endocinol | 2014 | Timing of hCG administration | Oocytes retrieved | 7 |
| Lin | PlosONE | 2014 | GnRH agonist vs. GnRH antagonist | Pregnancy rate | 9 |
| Hu | J Int Med Res | 2014 | LH priming vs. FSH alone | Estradiol serum levels | 3 |
| Song | Gynecol Endocinol | 2014 | GnRH agonist vs. letrozole | Pregnancy rate | 3 |
| Siristatidis | Cochrane Database Syst Rev | 2015 | different GnRH agonist protocols | Pregnancy rate | 37 |
| Weiss | Cochrane Database Syst Rev | 2015 | U-FSH vs. r-FSH in PCOS | Live birth rate | 14 |
| Nugent | Cochrane Database Syst Rev | 2015 | Different u-FSH in PCOS | Withdrawan | |
| Nahuis | Cochrane Database Syst Rev | 2015 | U-FSH vs. r-FSH in PCOS | Withdrawan | |
| Pandian | Cochrane Database Syst Rev | 2015 | IVF vs. IUI | Pregnancy rate | 8 |
| Pouwer | Cochrane Database Syst Rev | 2015 | Long acting FSH vs. r-FSH | Live birth rate | 6 |
| Youssef | J Adv Res | 2015 | GnRH agonist vs. hCG for trigger | Pregnancy rate | 19 |
| Fensore | J Ovar Res | 2015 | Long acting FSH vs. r-FSH | Oocytes retrieved | 7 |
| Al-Inany | Cochrane Database Syst Rev | 2016 | GnRH agonist vs. GnRH antagonist | Live birth rate | 63 |
| Youssef | Cochrane Database Syst Rev | 2016 | U-hCG vs. r-hCG | Live birth rate | 18 |