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. 2017 Mar 23;122(5):1336–1350. doi: 10.1152/japplphysiol.00703.2016

Fig. 1.

Fig. 1.

Body weight and fiber-type-specific cross-sectional area (CSA) changes in adult and old rats in response to hindlimb unloading (HU). A: average starting body weight for adult (9 mo) and old (29 mo) male F344BN rats. B: loss of body weight in adult and old rats after 3, 7, and 14 days of HU. All values are expressed as percent loss from age-matched control animals for each HU time point. Changes in fiber-type-specific CSA were measured in the TA (C) and soleus (D) of adult (open bars) and old (solid bars) rats at baseline (control) and after 14 days of HU (n = 3–6/group). Values are means ± SE. *P < 0.05 vs. adult control. #P < 0.05 vs. old control. ϕP < 0.05 vs. adult at same time point. Fiber-type compositions of the adult and old rat TA (E) and soleus (F) were calculated at baseline (control) and after 14 days of HU. The no. of each fiber type was counted and expressed as a percentage of the total number of fibers.