Table 2.
Control (n = 18) | CKD (n = 31) | P Value | |
---|---|---|---|
Baseline arterial diameter, mm | 4.00 ± 0.12 | 4.43 ± 0.08 | 0.003 |
Baseline blood velocity, m/s | 0.94 ± 0.06 | 0.76 ± 0.02 | 0.002 |
Baseline shear rate, s−1 × 103 | 0.97 ± 0.07 | 0.70 ± 0.03 | <0.001 |
Hyperemic arterial diameter, mm | 4.23 ± 0.14 | 4.54 ± 0.08 | 0.041 |
Hyperemic blood velocity, m/s | 1.76 ± 0.06 | 1.41 ± 0.04 | <0.001 |
Hyperemic shear rate, s−1 × 103 | 1.71 ± 0.10 | 1.26 ± 0.05 | <0.001 |
FMD, % | 5.84 ± 0.97 | 2.76 ± 0.42 | 0.001 |
FMDshear, %/(s−1 × 103) | 3.72 ± 0.62 | 2.23 ± 0.35 | 0.043 |
Values are expressed as means ± SE. FMD %, flow-mediated dilation as % change from baseline diameter. Normalized FMD, FMDshear, was adjusted for peak hyperemic shear rate.