Fig. 8.

Inhibiting K_IR channels results in pressure-dependent constriction of bladder feed arterioles. A, B: representative tracings of bladder feed arteriolar responses to increases in intraluminal pressure in the absence (A) or presence (B) of BaCl₂ (100 µM). Vessels dilated to a diameter equivalent to controls after removal of BaCl₂ at 80 mmHg. C: summary graph showing that BaCl₂ resulted in pressure-induced constriction of bladder feed arterioles, indicating that K_IR channel inhibition results in myogenic constriction. *P < 0.05 vs. control; N = 3.