Fig. 9.

K_IR channel currents in isolated bladder arteriolar smooth muscle cells from K_IR2.1^SMKO mice. A: without tamoxifen treatment, isolated bladder arteriole myocytes from K_IR2.1^SMKO mice exhibited Ba²⁺-sensitive inward-rectifying currents. With tamoxifen treatment, Ba²⁺-sensitive currents were nearly abolished. B: summary graph of Ba²⁺-sensitive inward current densities (at a membrane potential of −140 mV) from K_IR2.1^SMKO mice. In both A and B, currents from C57Bl/6 mice are shown for comparison (see Fig. 5). *P < 0.05; n = 6–11 cells from N = 2–3 mice.