Table 2.

In vivo structural and functional cardiac parameters measured by echocardiography in Sham and RUPP rats at 8 wk postpartum

	Sham (n = 9)*	RUPP (n = 19)*	P Value
Heart weight, g	0.85 ± 0.07	0.89 ± 0.07	0.185
Structural
LV mass, mg	789 ± 166	812 ± 141	0.707
LV mass/body weight, mg/g	2.9 ± 0.7	3.0 ± 0.5	0.646
LVPWd, mm	1.7 ± 0.5	1.7 ± 0.4	0.886
LVPWs, mm	2.6 ± 0.6	2.3 ± 0.5	0.274
LVAWd, mm	1.5 ± 0.3	1.6 ± 0.3	0.408
LVAWs, mm	2.5 ± 0.2	2.5 ± 0.3	0.741
LVIDd, mm	7.25 ± 0.64	7.12 ± 0.61	0.624
LVIDs, mm	4.34 ± 0.86	4.63 ± 0.54	0.278
LV VOLd, μl	278.8 ± 51.9	273.6 ± 36.7	0.761
LV VOLs, μl	89.3 ± 38.3	100.9 ± 26.0	0.355
Functional
HR, beats/min	337 ± 19	342 ± 23	0.613
CO, ml	63.7 ± 8.9	59.1 ± 11.1	0.300
Mean aortic velocity, mm/s	743 ± 167	982 ± 364	0.115
Peak aortic velocity, mm/s	1338 ± 332	1735 ± 593	0.115
Peak aortic gradient	7.6 ± 3.6	10.5 ± 5.8	0.235
MV E, mm/s	904 (741–927)	861 (602–912)	0.667
MV A, mm/s	659 (604–807)	653 (508–737)	1.000
MV E/A	1.3 ± 0.2	1.3 ± 0.1	0.957
IVRT, ms	19.2 ± 5.3	22.0 ± 6.3	0.318
IVCT, ms	21.1 ± 7.2	23.9 ± 7.3	0.415

Data are means ± SD or medians (25–75 percentile). LV, left ventricle; LVPWd and LVPWs, left ventricular posterior wall during end diastole and end systole; LVAWd and LVAWs, left ventricular anterior wall during end diastole and end systole; LVIDd and LVIDs, left ventricular internal diameter end diastole and end systole; LV VOLd and LV VOLs, left ventricular volume during diastole and systole HR, heart rate; CO, cardiac output; MV E, peak mitral valve (MV) early filling; MV A, peak MV active filling; MV E/A, MV early-to-active filling ratio; IVRT, isovolumetric relaxation time; IVCT, isovolumetric contraction time

^*Total number of rats in each group, all parameters were successful in at least 70% of the animals.