Table 3.
Macroscopic and microscopic features of kidney in Sham and RUPP rats at 8 wk postpartum
| Sham (n = 12) | RUPP (n = 21) | P Value | |
|---|---|---|---|
| Left kidney weight, g | 0.72 ± 0.08 | 0.70 ± 0.04 | 0.443 |
| Right kidney weight, g | 0.73 ± 0.07 | 0.75 ± 0.06 | 0.526 |
| Glomerular area, pixels × 103 | 243 ± 27 | 241 ± 28 | 0.885 |
| Glomerular damage, %glomeruli | |||
| None | 77.1 ± 7.5 | 77.1 ± 6.3 | 0.921 |
| Partial | 22.7 ± 7.4 | 22.1 ± 6.5 | |
| Total | 0.2 ± 0.6 | 0.2. ± 0.6 | |
| Tubulo-interstitial infiltrate score | 0.03 (0.00–0.06) | 0.00 (0.00–0.06) | 0.765 |
| Tubulo-interstitial fibrosis score | 0.11 (0.05–0.15) | 0.10 (0.00–0.17) | 0.765 |
| Tubulo-interstitial atrophy score | 0.06 (0.00–0.12) | 0.06 (0.00–0.10) | 0.866 |
| JG12+, %glomerular area | 23 ± 4 | 25 ± 7 | 0.518 |
Data are means ± SD or medians (25–75 percentile).