Fig. 6.

Macrophage infiltration in the kidney promotes inflammation. A: F4/80 expression was increased in glomeruli of the kidney. Immunostaining for F4/80 showed increased expression in glomeruli of the kidney, supporting macrophage-mediated infiltration and promotion of inflammation in hypertensive mice (white arrows). B: TNF-α expression was increased in glomeruli and tubular areas of the kidney. IL-10 was low in hypertensive mice but elevated in kidneys of mice treated with GYY, supporting Western blot data (white arrows). Magnification: ×60. Scale bars = 40 µm.