Fig. 2.

Effect of macrolides ± cigarette smoke extract (CSE) on the phagocytic capacity of primary human alveolar macrophages. Phagocytosis of nontypeable Haemophilus influenzae (A) and efferocytosis of apoptotic bronchial epithelial cells (B). GS-459755 (G4) and GS-560660 (G5) were used at concentrations of 0.5 and 1 µg/ml; n = 5 experiments performed in triplicate. *P < 0.05 vs. control; †P < 0.05 vs. CSE, unless otherwise indicated. Data presented as box plots, as described in Fig. 1, and analyzed using Friedman and Wilcoxon signed-rank tests.