Fig. 5.
Effect of macrolides on THP-1 macrophage viability. Cells were treated with GS-459755 (GS4) and GS-560660 (GS5) and then stained with the apoptotic marker Annexin V (A) or the cell death marker Sytox Green (B) and analyzed using flow cytometry; n = 5 experiments performed in triplicate. Data presented as box plots, as described in Fig. 1, and analyzed using Friedman and Wilcoxon signed-rank tests.