Table 1. BED10 for SIF and CF models using different alpha, tumor kick off and tumor doubling times parameters.
Alpha (Gy-1) | Tpot (days) | TK =21 days | TK =28 days | TK =35 days | |||||
---|---|---|---|---|---|---|---|---|---|
SIF | CF | SIF | CF | SIF | CF | ||||
0.2 | 3 | 75.2 | 52.3 | 83.3 | 61.9 | 91.4 | 71.6 | ||
4.5 | 80.6 | 68.4 | 86 | 74.8 | 91.4 | 81.3 | |||
6 | 83.3 | 76.4 | 87.4 | 81.3 | 91.4 | 86.1 | |||
0.3 | 3 | 80.6 | 68.4 | 86 | 74.8 | 91.4 | 81.3 | ||
4.5 | 84.2 | 79.1 | 87.8 | 83.4 | 91.4 | 87.7 | |||
6 | 86 | 84.5 | 88.7 | 87.7 | 91.4 | 90.9 | |||
0.4 | 3 | 83.6 | 76.4 | 87.4 | 81.3 | 91.4 | 86.1 | ||
4.5 | 86 | 84.5 | 88.7 | 87.7 | 91.4 | 90.9 | |||
6 | 87.4 | 88.5 | 89.4 | 90.9 | 91.4 | 93.3 |
CF, conventionally fractionated schedule; SIF, short integrated fractionation schedule; BED, biologically effective dose; TK, tumor kick off time to accelerated repopulation in days for the start of accelerated repopulation; Tpot, potential tumor Doubling time in days