Table 3.
Signal transduction pathway | Proportion | |
---|---|---|
Interferon signaling | GBP1, IFNG, IL6 | 3/4 |
Interferon-responsive genes | CCL2 (MCP-1), CCL5 (RANTES), CXCL10 (IP-10), GBP1 | 4/10 |
NFκB targets | CCL2 (MCP-1), CCL5 (RANTES), CSF1 (MCSF), IFNG | 4/9 |
STAT targets | CCL2 (MCP-1), CCL4 (MIP-1B), CCL5 (RANTES), CSF1 (MCSF), CXCL10 (IP-10), CXCL11 (I-TAC, IP-9), IL1B, IL6 | 8/17 |
Transcription factors | FOXP3, STAT3 | 2/8 |