Figure 10. Diversity of firing following a depolarizing current injection.

A, sample voltage traces in response to a 10 pA, 500 ms depolarizing current injection from a set pre‐stimulus membrane potential of −80 mV. Different neurons display diverse firing outcomes for this stimulus, including (Aa) high frequency bursting and (Ab) regular firing. B, heterogeneity of firing behaviour in response to a 60 pA depolarizing current step. Each row represents a different neuron and the time at which the first AP is generated for each neuron is represented by a black point at 0 ms. The timing of all subsequent APs generated is plotted relative to the first spike. The second spike is represented by a red point, the third by dark yellow, the fourth by yellow and the fifth by green, etc. Representing the data in this form illustrates the diverse array of different firing patterns present in the neuronal population.