Table 2.
Relationship between the expression of LAMP3 and clinicopathological characteristics in OSCC.
| Characteristic | n | Low expression (%) | High expression (%) | Pearson χ2 | P | |
|---|---|---|---|---|---|---|
| Total | 248 | 186 (75.00) | 62 (25.00) | |||
| Gender | Male | 115 | 88 (76.52) | 27 (23.48) | 0.265 | 0.607 |
| Female | 133 | 98 (73.68) | 35 (26.32) | |||
| Age | <60 | 110 | 79 (71.82) | 31 (28.18) | 1.067 | 0.302 |
| ≥60 | 138 | 107 (77.54) | 31 (22.46) | |||
| Tobacco consumption | No | 134 | 98 (73.13) | 36 (26.87) | 0.541 | 0.462 |
| Yes | 114 | 88 (77.19) | 26 (22.81) | |||
| Alcohol consumption | No | 132 | 97 (73.48) | 35 (26.52) | 0.346 | 0.557 |
| Yes | 116 | 89 (76.72) | 27 (23.38) | |||
| Tumor location | Buccal | 107 | 77 (71.96) | 30 (28.04) | 0.926 | 0.336 |
| Tongue | 141 | 109 (77.30) | 32 (22.70) | |||
| Differentiation | Poor | 102 | 85 (83.33) | 17 (16.67) | 6.417 | 0.011∗ |
| Moderate and well | 146 | 101 (69.18) | 45 (30.28) | |||
| TNM stage | 0-I | 95 | 76 (80.00) | 19 (20.00) | 6.305 | 0.043∗ |
| II-III | 73 | 58 (79.45) | 15 (20.55) | |||
| IV | 80 | 52 (65.00) | 28 (35.00) | |||
| T | Tis-T1 | 110 | 82 (74.55) | 28 (25.45) | 0.486 | 0.784 |
| T2 | 58 | 42 (72.41) | 16 (27.59) | |||
| T3-T4 | 80 | 62 (77.50) | 18 (22.50) | |||
| Node metastasis | No | 193 | 150 (77.72) | 43 (22.28) | 3.434 | 0.064 |
| Yes | 55 | 36 (65.45) | 19 (34.55) | |||
∗ P < 0.05.